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1996年10月至1997年6月英格兰和威尔士的流感监测

Influenza surveillance in England and Wales: October 1996 to June 1997.

作者信息

Dedman D J, Joseph C A, Zambon M, Fleming D M, Watson J M

机构信息

PHLS Communicable Disease Surveillance Centre, London.

出版信息

Commun Dis Rep CDR Rev. 1997 Dec 12;7(13):R212-9.

PMID:9447787
Abstract

This report summarises information collected for the surveillance of influenza in England and Wales during the winter of 1996/97. Consultations for 'influenza and influenza-like illness' with sentinel general practitioners in England and Wales began to increase towards the end of November and peaked at the start of January. In England, consultations for 'aggregated respiratory disease' (ARD) began to increase a little earlier, perhaps as a result of increased respiratory syncytial virus activity, but also peaked in early January. Influenza A (H3N2) viruses were first detected in early October, but rarely until November, and activity peaked in early January, coinciding with the peak in consultations for flu-like illness. A few influenza B viruses were detected in late November and early December, and substantial activity was recorded in mid-January. Approximately equal numbers of influenza A(H3N2) and B viruses were identified over the winter as a whole, and circulating strains were antigenically similar to those included in the vaccine for 1996/97. Although influenza activity was 'moderate' in terms of consultations and laboratory confirmed infections, a large peak in death registrations occurred at the same time as influenza A(H3N2) virus activity peaked. The number of deaths during the winter was similar to that seen in 1989/90, when the last severe influenza epidemic occurred in England and Wales.

摘要

本报告总结了1996/97年冬季在英格兰和威尔士收集的流感监测信息。在英格兰和威尔士,向哨点全科医生咨询“流感及流感样疾病”的人数在11月底开始增加,并于1月初达到峰值。在英格兰,“聚合性呼吸道疾病”(ARD)的咨询人数增加得稍早一些,这可能是呼吸道合胞病毒活动增加的结果,但也在1月初达到峰值。甲型(H3N2)流感病毒于10月初首次被检测到,但直到11月才很少出现,其活动在1月初达到峰值,与流感样疾病咨询人数的峰值一致。11月底和12月初检测到少量乙型流感病毒,1月中旬记录到大量病毒活动。整个冬季,甲型(H3N2)流感病毒和乙型流感病毒的数量大致相等,并且流行毒株在抗原性上与1996/97年疫苗中包含的毒株相似。尽管从咨询人数和实验室确诊感染情况来看,流感活动为“中度”,但在甲型(H3N2)流感病毒活动达到峰值的同时,死亡登记出现了一个大高峰。冬季的死亡人数与1989/90年相似,当时英格兰和威尔士上一次发生了严重的流感疫情。

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