Wenzel F G, Horn T D
Department of Dermatology, The Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA.
J Am Acad Dermatol. 1998 Jan;38(1):1-17; quiz 18-20. doi: 10.1016/s0190-9622(98)70532-8.
Eccrine glands are uniquely susceptible to a variety of pathologic processes. Alteration in the rate of sweat secretion manifests as hypohidrosis and hyperhidrosis. Obstruction of the eccrine duct leads to miliaria. The excretion of drugs into eccrine sweat may be a contributory factor in neutrophilic eccrine hidradenitis (NEH), syringosquamous metaplasia (SSM), coma bulla, and erythema multiforme (EM). Alterations in the electrolyte composition of eccrine sweat can be observed in several systemic diseases, most notably cystic fibrosis. This article summarizes current knowledge of eccrine gland pathophysiology.
小汗腺对多种病理过程具有独特的易感性。汗液分泌速率的改变表现为少汗症和多汗症。小汗腺导管阻塞会导致粟丘疹。药物排泄到小汗腺汗液中可能是嗜中性小汗腺汗腺炎（NEH）、汗腺鳞状化生（SSM）、昏迷水疱和多形红斑（EM）的一个促成因素。在几种全身性疾病中可以观察到小汗腺汗液电解质组成的改变，最显著的是囊性纤维化。本文总结了目前关于小汗腺病理生理学的知识。
