Tohen M, Zarate C A
Bipolar and Psychotic Disorders Program, McLean Hospital, Belmont, MA 02178, USA.
J Clin Psychiatry. 1998;59 Suppl 1:38-48; discussion 49.
Antipsychotic agents have been used commonly in the treatment of bipolar disorder. This article reviews the evolution of the use of antipsychotic agents and their role in the acute and maintenance treatment of bipolar disorder. The focus is on neuroleptic drugs, the atypical antipsychotic drugs (risperidone and clozapine), and two fo the new atypical antipsychotic drugs that were recently approved.
抗精神病药物已普遍用于双相情感障碍的治疗。本文回顾了抗精神病药物的使用演变及其在双相情感障碍急性和维持治疗中的作用。重点是抗精神病药物、非典型抗精神病药物（利培酮和氯氮平）以及最近获批的两种新型非典型抗精神病药物。
