Rodrigo M R
Int Dent J. 1997 Feb;47(1):32-8. doi: 10.1111/j.1875-595x.1997.tb00675.x.
Having gained knowledge of the advantages of inhalational and intravenous sedation many dental practitioners use these techniques to supplement local anaesthesia for dental procedures. Inhalational sedation is commonly carried out with nitrous oxide and oxygen while isoflurane in oxygen has also been tried out. Intravenous sedation is commonly carried out with midazolam or diazepam given as a single titrated dose to an end point which does not result in anaesthesia. When sedation with benzodiazepines is carried out, the specific antagonist, flumazenil should always be available for use in emergencies such as accidental oversedation, iatrogenic overdose or paradoxical reactions. Patient controlled sedation with midazolam, the modern technique of intravenous sedation, is comparable to anaesthetist controlled sedation and patients may be administered increments of one milligram at one minute intervals. Computer controlled sedation has been carried out with propofol. Mortality following sedation is low in the United Kingdom, partly due to the strict guidelines of the General Dental Council in the United Kingdom.
许多牙科医生了解到吸入性镇静和静脉镇静的优势后,便使用这些技术来辅助牙科手术中的局部麻醉。吸入性镇静通常使用一氧化二氮和氧气进行,同时也尝试过氧气与异氟烷的组合。静脉镇静通常使用咪达唑仑或地西泮,以单次滴定剂量给药至未导致麻醉的终点。使用苯二氮䓬类药物进行镇静时,特定拮抗剂氟马西尼应随时可用,以应对意外过度镇静、医源性过量或反常反应等紧急情况。咪达唑仑患者自控镇静作为现代静脉镇静技术,与麻醉师控制的镇静效果相当,患者可每隔一分钟给予1毫克增量。丙泊酚已用于计算机控制的镇静。在英国,镇静后的死亡率较低,部分原因是英国牙科总会的严格指导方针。