Berridge J K, Morgan D A
Department of Clinical Oncology, Nottingham City Hospital, UK.
Clin Oncol (R Coll Radiol). 1997;9(6):400-2. doi: 10.1016/s0936-6555(97)80137-9.
Fractionated superficial X-ray therapy and gold grain brachytherapy Elastoplast mould (EPM) methods of treating basal cell carcinoma (BCC) on facial skin were compared for long term cosmesis. Thirty patients were traced who had been treated successfully for a BCC on the face more than ten years previously. Late skin and subcutaneous changes were graded. Fifteen had been treated with 116 kV X-rays (32.5 Gy in five fractions on 5 consecutive days, and the remaining 15 with radioactive gold EPMs, delivering a dose of 6000-6500 R with an application lasting 7 days). The late cosmetic result scores of the patients treated by X-rays gave a mean score of 2.13; only three of these patients had a score of less than 2. The mean score for the patients treated with EPMs was 1.47; none had a score greater than 2. The difference is statistically significant (P < 0.01, Wilcoxon rank sum test). The EPM gave much more acceptable late cosmetic results.
为了长期的美容效果,对分次浅表X线治疗和金粒近距离放射治疗弹性绷带模具(EPM)治疗面部皮肤基底细胞癌(BCC)的方法进行了比较。追踪了30例患者,他们在十多年前面部BCC治疗成功。对晚期皮肤和皮下变化进行分级。15例接受116 kV X线治疗(连续5天分5次给予32.5 Gy,其余15例接受放射性金EPM治疗,给予6000 - 6500 R剂量,敷贴7天)。X线治疗患者的晚期美容效果评分为2.13;这些患者中只有3例评分低于2分。EPM治疗患者的平均评分为1.47;没有患者评分大于2分。差异具有统计学意义(P < 0.01,Wilcoxon秩和检验)。EPM的晚期美容效果更易接受。