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Histochemical observations on enzymatic processes in bones and teeth.骨骼和牙齿酶促过程的组织化学观察
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Stage-specific expression patterns of alkaline phosphatase during development of the first arch skeleton in inbred C57BL/6 mouse embryos.近交系C57BL/6小鼠胚胎第一鳃弓骨骼发育过程中碱性磷酸酶的阶段特异性表达模式。
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An immunohistochemical study of regional differences in the distribution of type I and type II collagens in rat mandibular condylar cartilage.大鼠下颌髁突软骨中I型和II型胶原蛋白分布区域差异的免疫组织化学研究
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The expression of types X and VI collagen and fibrillin in rat mandibular condylar cartilage. Response to mastication forces.大鼠下颌髁突软骨中X型和VI型胶原蛋白及原纤维蛋白的表达。对咀嚼力的反应。
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Arch Oral Biol. 1996 Jan;41(1):127-31. doi: 10.1016/0003-9969(95)00102-6.
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A histological study of the developing condylar cartilage of the fetal mouse mandible using coronal sections.利用冠状切片对胎鼠下颌髁突软骨发育进行的组织学研究。
Arch Oral Biol. 1996 Jan;41(1):47-54. doi: 10.1016/0003-9969(95)00105-0.
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Initiation of secondary cartilage in the mandible of the Syrian hamster in the absence of muscle function.在无肌肉功能的情况下叙利亚仓鼠下颌骨中次级软骨的起始。
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Type II collagen expression in the mandibular condyle during growth adaptation: an experimental study in the rabbit.生长适应过程中兔下颌髁突Ⅱ型胶原的表达：一项实验研究
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胎鼠下颌髁突软骨发育过程中Ⅱ型和X型胶原蛋白的免疫组织化学及碱性磷酸酶的酶组织化学研究

Immunohistochemistry of collagen types II and X, and enzyme-histochemistry of alkaline phosphatase in the developing condylar cartilage of the fetal mouse mandible.

作者信息

Shibata S, Fukada K, Suzuki S, Yamashita Y

机构信息

1st Department of Oral Anatomy, School of Dentistry, Tokyo Medical and Dental University, Japan.

出版信息

J Anat. 1997 Nov;191 ( Pt 4)(Pt 4):561-70. doi: 10.1046/j.1469-7580.1997.19140561.x.

DOI:10.1046/j.1469-7580.1997.19140561.x
PMID:9449075
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1467723/
Abstract

We investigated the immunohistochemical localisation of types II and X collagen as well as the cytochemical localisation of alkaline phosphatase in the developing condylar cartilage of the fetal mouse mandible on d 14-16 of pregnancy. On d 14 of pregnancy, although no immunostaining for types II and X collagen was observed, alkaline phosphatase activity was detected in all cells in the anlage of the future condylar process. On d 15 of pregnancy, immunostaining for both collagen types was simultaneously detected in the primarily formed condylar cartilage. Alkaline phosphatase activity was also detected in chondrocytes at this stage. By d 16 of pregnancy, the hypertrophic cell zone rapidly increased in size. These findings strongly support a periosteal origin for the condylar cartilage of the fetal mouse mandible, and show that progenitor cells for condylar cartilage rapidly or directly differentiate into hypertrophic chondrocytes.

摘要

我们研究了妊娠第14 - 16天胎鼠下颌髁突软骨发育过程中II型和X型胶原蛋白的免疫组织化学定位以及碱性磷酸酶的细胞化学定位。妊娠第14天，虽然未观察到II型和X型胶原蛋白的免疫染色，但在未来髁突原基的所有细胞中检测到碱性磷酸酶活性。妊娠第15天，在初步形成的髁突软骨中同时检测到两种胶原蛋白类型的免疫染色。此阶段软骨细胞中也检测到碱性磷酸酶活性。到妊娠第16天，肥大细胞区迅速增大。这些发现有力地支持了胎鼠下颌髁突软骨起源于骨膜的观点，并表明髁突软骨的祖细胞迅速或直接分化为肥大软骨细胞。