莫扎比特人中的血红蛋白D-乌尔德·拉巴赫：一种追溯说柏柏尔语人群起源的相关变体。

Haemoglobin D-Ouled Rabah among the Mozabites: a relevant variant to trace the origin of Berber-speaking populations.

作者信息

Merghoub T, Sanchez-Mazas A, Tamouza R, Lu C Y, Bouzid K, Ardjoun F Z, Labie D, Lapouméroulie C, Elion J

机构信息

INSERM U458, Hôpital Robert-Debré, Paris, France.

出版信息

Eur J Hum Genet. 1997 Nov-Dec;5(6):390-6.

PMID:9450184

Abstract

We have studied haemoglobin (Hb) variants and blood groups (ABO, RH, and Kell) in 598 children from the Berber population of the Mzab. Hb D-Ouled Rabah, considered as a private marker of the Kel Kummer Tuaregs, and Hb C were found at the same gene frequency (0.015). Haplotype analysis suggests a single origin to the Hb D mutation. Genetic distances calculated from the blood group data cluster Mozabites and Tuaregs with the other Berber-speaking groups, Arabic-speaking populations being more distant. But, we found no specific relationship between Mozabites and Kel Kummers. Tuaregs in general exhibit features that tend to differentiate them from other Berber-speaking groups. Hb D-Ouled Rabah may be specific of Berber-speaking populations.

摘要

我们研究了姆扎卜柏柏尔人群中598名儿童的血红蛋白（Hb）变体和血型（ABO、RH和凯尔血型）。被视为凯尔库默图阿雷格人特有标记的Hb D-乌尔德·拉巴赫和Hb C以相同的基因频率（0.015）被发现。单倍型分析表明Hb D突变有单一起源。根据血型数据计算出的遗传距离将姆扎卜人和图阿雷格人与其他说柏柏尔语的群体聚类在一起，说阿拉伯语的人群则距离更远。但是，我们没有发现姆扎卜人和凯尔库默人之间有特定关系。一般来说，图阿雷格人表现出一些使其有别于其他说柏柏尔语群体的特征。Hb D-乌尔德·拉巴赫可能是说柏柏尔语人群所特有的。