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同卵双胞胎和异卵双胞胎在身体生长方面的一致性。

Concordance in physical growth for monozygotic and dizygotic twins.

作者信息

Wilson R S

出版信息

Ann Hum Biol. 1976 Jan;3(1):1-10. doi: 10.1080/03014467600001091.

Abstract

Heights and weights were analysed for 636 twins who had been repeatedly measured from birth to 4 years. MZ twins were less concordant for birth weight than DZ twins, principally as a result of a few MZ pairs who exhibited very large differences. By one year of age, however, MZ twins had become more concordant for weight (Rmz = 0-87) while DZ twins moved further apart (Rdz = 0-55). For height, at birth, the MZ correlation was 0-58 while the DZ correlation was 0-82, but by 2 years, the MZ correlation reached 0-89 and the DZ correlation regressed to 0-58. The actual size differences within pairs followed a parallel course--for MZ twins, the differences became smaller following birth, whereas DZ differences became larger. The results are discussed in terms of (a) prenatal influences that differntially affect birth size within MZ pairs and DZ pairs, and (b) the rapid convergence of each twin on his genetic growth curve.

摘要

对636对双胞胎从出生到4岁进行了多次身高和体重测量。同卵双胞胎在出生体重上的一致性不如异卵双胞胎,主要是因为有几对同卵双胞胎体重差异非常大。然而,到1岁时,同卵双胞胎在体重上的一致性更高(同卵双胞胎相关系数Rmz = 0.87),而异卵双胞胎的体重差异则进一步增大(异卵双胞胎相关系数Rdz = 0.55)。对于身高,出生时,同卵双胞胎的相关性为0.58,而异卵双胞胎的相关性为0.82,但到2岁时,同卵双胞胎的相关性达到0.89,异卵双胞胎的相关性则降至0.58。双胞胎对之间实际的体型差异呈现出相似的变化趋势——对于同卵双胞胎,出生后差异变小,而异卵双胞胎的差异则变大。研究结果从以下两个方面进行了讨论:(a)对同卵双胞胎对和异卵双胞胎对出生时体型产生不同影响的产前因素;(b)每个双胞胎迅速趋向于其遗传生长曲线的情况。

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