Seggie J, Brown G M
Endocrinology. 1976 Jun;98(6):1516-22. doi: 10.1210/endo-98-6-1516.
Diurnal variation in resting prolactin levels was studied in male rats that were normal, sham-operated, or lesioned in the septal nuclei. Separate groups of rats were sampled by decapitation every 3 or 4 hours in two separate studies during a 24 h period consisting of 12 h light and 12 h dark. Male rats did not exhibit a significant diurnal variation in resting prolactin levels. A septal lesion had no effect on resting prolactin levels. Prolactin levels were found to be highly responsive to environmental disturbances and were subject to the effects of sequential sacrificing procedures. The possibility was raised that prolactin exhibits a diurnal variation in sensitivity to stress which varies as a function of circulating levels of corticosterone.
在正常、假手术或隔核损伤的雄性大鼠中研究了静息催乳素水平的昼夜变化。在由12小时光照和12小时黑暗组成的24小时期间，通过两项单独的研究，每隔3或4小时对不同组的大鼠进行断头取样。雄性大鼠静息催乳素水平未表现出显著的昼夜变化。隔核损伤对静息催乳素水平没有影响。发现催乳素水平对环境干扰高度敏感，并受连续处死程序的影响。有人提出，催乳素对应激的敏感性存在昼夜变化，这种变化随皮质酮循环水平而变化。
