Janszky I, Szedmák S, Istók R, Kopp M
Institute of Behavioural Sciences, Semmelweis University of Medicine, Budapest, Hungary.
Int J Psychophysiol. 1997 Dec;27(3):249-52. doi: 10.1016/s0167-8760(97)00056-1.
In recent years the role of hyperventilation in the generation of panic attacks has attracted a considerable amount of interest. According to these studies hyperventilation can elicit the somatic symptoms of panic due to systemic alkalosis. We suggest that since in the case of panic, sweating might cause alkalosis, it could also contribute to the generation of panic attacks. In light of this hypothesis we made a statistical analysis of the panic symptoms of 111 panic patients diagnosed according to DSM-III criteria. The analysis revealed that: (1) there was a well identified group of panic patients who had minor breathing difficulties with heavy sweating; and (2) that all the patients sampled had either severe breathing, or sweating symptoms, or both. We conclude that in the absence of the intensive physical activity of the 'flight or fight' reaction, sweating as well as hyperventilation can cause alkalosis, which in turn might generate panic attacks.
近年来，过度换气在恐慌症发作中的作用引起了相当大的关注。根据这些研究，过度换气可因全身性碱中毒引发恐慌的躯体症状。我们认为，在恐慌症患者中，出汗可能会导致碱中毒，这也可能促使恐慌症发作。基于这一假设，我们对111名根据《精神疾病诊断与统计手册》第三版（DSM-III）标准确诊的恐慌症患者的恐慌症状进行了统计分析。分析结果显示：（1）有一组明确的恐慌症患者存在轻微呼吸困难并伴有大量出汗；（2）所有抽样患者都有严重的呼吸症状或出汗症状，或两者皆有。我们得出结论，在没有“战斗或逃跑”反应所伴随的剧烈身体活动的情况下，出汗以及过度换气都会导致碱中毒，进而可能引发恐慌症发作。
