Puech A J, Simon P, Boissier J R
Eur J Pharmacol. 1976 Apr;36(2):439-41. doi: 10.1016/0014-2999(76)90098-4.
Three effects of apomorphine (hypothermia and climbing behavior in mice, stereotyped behavior in rats) were studied. Sulpiride antagonized the two effects in mice but stereotyped behavior in rats remained unchanged. Pimozide and haloperidol antagonized the three effects. These results could be explained by the existence of two types of dopaminergic receptors or by the different accessibility to identical dopaminergic receptors located in different CNS areas.
研究了阿扑吗啡的三种效应（小鼠体温过低和攀爬行为、大鼠刻板行为）。舒必利拮抗了小鼠的两种效应，但大鼠的刻板行为未改变。匹莫齐特和氟哌啶醇拮抗了这三种效应。这些结果可以通过存在两种类型的多巴胺能受体来解释，或者通过位于不同中枢神经系统区域的相同多巴胺能受体具有不同的可及性来解释。
