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[上巴伐利亚州黇鹿和野生马鹿的地方性脊髓共济失调]

[Enzootic spinal ataxia in fallow and wild red deer in Upper Bavaria].

作者信息

Geisel O, Betzl E, Dahme E, Schmahl W, Hermanns W

机构信息

Institut für Tierpathologie, Ludwig-Maximilians-Universität München.

出版信息

Tierarztl Prax Ausg G Grosstiere Nutztiere. 1997 Nov;25(6):598-604.

PMID:9451765
Abstract

Since 1993 several cases of spinal ataxia occurred in adult red and/or fallow deer in four farms in Southern Bavaria. The disease based on a secondary copper deficiency due to a high level of molybden and a low level of copper content in the feed. Some of the animals suffer from a severe disturbance of motion. In most cases the animals are shot at the beginning of illness. Histologically the most important lesions are in the spinal cord consisting mainly in a bilateral symmetric degeneration of dorsolateral and ventral areas of the white matter. Degeneration is caused by lamellar disintegration of the myelin connected with deposition of fine-granulated substances detectable by electronmicroscopical investigation. In the liver and other organs we always found a hemosiderosis which is also believed to be caused by copper deficiency.

摘要

自1993年以来,巴伐利亚南部四个农场的成年马鹿和/或黇鹿出现了几例脊髓共济失调病例。该病是由于饲料中钼含量高、铜含量低导致继发性铜缺乏引起的。一些动物患有严重的运动障碍。大多数情况下,动物在发病初期就被射杀。组织学上,最重要的病变在脊髓,主要表现为白质背外侧和腹侧区域的双侧对称性变性。变性是由髓鞘的层状崩解引起的,伴有电子显微镜检查可检测到的细颗粒物质沉积。在肝脏和其他器官中,我们总是发现有含铁血黄素沉着症,这也被认为是由铜缺乏引起的。

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