Wesche J, Orning O, Eriksen M, Walløe L
Department of Physiology, University of Oslo, Norway.
Cardiology. 1998;89(1):73-5. doi: 10.1159/000006746.
Beat-by-beat heart rate (HR) changes during exercise were studied in two young and fit heart-transplanted humans at different time intervals following transplantation. Upon the start of the exercise, a slow gradual increase in HR was seen during the early experiments after the transplantation, whereas an immediate rapid increase in HR was observed during the later experiments. From standard ECGs obtained 32 months after transplantation, two P waves at somewhat different rates could be identified in both subjects, probably arising from donor and recipient sinoatrial nodes, respectively. The two P wave rate changes during and following exercise were very similar. We conclude that these changes in the HR pattern and ECG must be due to reinnervation of the donor hearts, most likely by parasympathetic cardiac fibers.
在两名年轻且健康的心脏移植患者中，研究了移植后不同时间间隔运动期间逐搏心率（HR）的变化。运动开始时，移植后的早期实验中HR出现缓慢逐渐增加，而后期实验中则观察到HR立即快速增加。从移植后32个月获得的标准心电图中，两名受试者均能识别出两个速率略有不同的P波，可能分别来自供体和受体的窦房结。运动期间及运动后两个P波速率的变化非常相似。我们得出结论，HR模式和心电图的这些变化一定是由于供体心脏的重新神经支配，很可能是由副交感神经心脏纤维所致。
