Gotoh Y, Kubota M, Kaseno S, Furukawa K
Hokkaido Igaku Zasshi. 1976 Mar;51(2):123-8.
In recent years application of computer techniques to various problems in biology has increased. In the field of anesthesia, where rapid changes appearing in a short time must be followed, the conventional, mannual methods are not applicable. So we have developed on-line computer analytical methods of cardiovascular function. Hybrid systems are the preferred methods in many biological problems, either because of efficiency and lower cost, or because of real time, on-line, closed-loop capabilities for direct use during experiments. As a computer output we used a graphic display computer and cathod ray tube devices. We applied these systems to analize and calculate cardiac work with other circulatory parameters. We got a ventricular function curve in visible form on CRT within 30 seconds after introducing the signals of left ventricular work and ventricular end-diastolic pressure into the analog computer. It was also useful to calculate vascular input impedence and myocardial maximal velocity of shortening. Finally causes of input errors in these analytical methods were discussed.
近年来,计算机技术在生物学各种问题上的应用有所增加。在麻醉领域,由于必须跟踪短时间内出现的快速变化,传统的手动方法并不适用。因此,我们开发了心血管功能的在线计算机分析方法。混合系统在许多生物学问题中是首选方法,要么是因为效率高和成本低,要么是因为具有实时、在线、闭环能力,可在实验期间直接使用。作为计算机输出,我们使用了图形显示计算机和阴极射线管设备。我们应用这些系统来分析和计算心脏做功以及其他循环参数。在将左心室做功和心室舒张末期压力信号输入模拟计算机后30秒内,我们在阴极射线管上以可见形式得到了心室功能曲线。计算血管输入阻抗和心肌最大缩短速度也很有用。最后讨论了这些分析方法中输入误差的原因。