A comparative study of the Crimean hemorrhagic fever-Congo group of viruses.

Twelve strains of the Crimean hemorrhagic fever (CHF)-Congo group of viruses the Bunyaviridae family were investigated with respect to sensitivity to lipid solvents and temperature, pathogenicity for animals, interactions with cell cultures and antigenic relationships. Complement fixation, agar gel diffusion and precipitation, immunofluorescence and neutralization tests showed Hazara virus to have a number of features distinguishing it from the other antigenic type of the CHF-Congo group.