Go R C, Duke L W, Harrell L E, Cody H, Bassett S S, Folstein M F, Albert M S, Foster J L, Sharrow N A, Blacker D
University of Alabama School of Public Health, Birmingham, USA.
J Geriatr Psychiatry Neurol. 1997 Oct;10(4):161-7. doi: 10.1177/089198879701000407.
As part of the NIMH Genetics Initiative Alzheimer's Disease (AD) Study Group, a brief structured telephone interview to distinguish individuals with normal cognitive functioning from those with changes in cognition and daily functioning suggestive of early AD was developed. The Structured Telephone Interview for Dementia Assessment (STIDA), yields a dementia score between 0 and 81 (higher scores indicating greater impairment). Subscales corresponding to the subscales of the Clinical Dementia Rating Scale (CDR) can be derived. The STIDA performed well as a screening instrument for mildly demented individuals. When a score of 10 or more (based on informant interview and subject testing) was used to identify mildly impaired individuals, the STIDA had a sensitivity of .93 and a specificity of .92 for a clinician-derived CDR of 0.5 or more. The STIDA was also capable of accurately assessing the level of dementia. STIDA-derived CDR ratings agreed with clinician-derived CDR scores in 23 of 28 cases, corresponding to an unweighted kappa of.71 and a weighted kappa of.81. A much-abbreviated short STIDA that could be administered directly to the subject was able to detect possible impairment with a sensitivity of .93 and a specificity of.77. These results suggest that the short STIDA provides a sensitive and fairly specific telephone screen for dementia, and that the full STIDA, consisting of an interview with a knowledgeable informant and subject testing, approximates the success of a face-to-face clinical interview, and provides reliable and valid screening and staging of dementia over the telephone.
作为美国国立精神卫生研究所（NIMH）遗传学倡议阿尔茨海默病（AD）研究小组的一部分，开发了一种简短的结构化电话访谈，以区分认知功能正常的个体与认知和日常功能发生变化提示早期AD的个体。痴呆评估结构化电话访谈（STIDA）得出的痴呆评分在0至81分之间（分数越高表明损害越严重）。可以得出与临床痴呆评定量表（CDR）各分量表相对应的分量表。STIDA作为轻度痴呆个体的筛查工具表现良好。当使用10分或更高的分数（基于知情者访谈和受试者测试）来识别轻度受损个体时，对于临床医生得出的CDR为0.5或更高的情况，STIDA的灵敏度为0.93，特异度为0.92。STIDA还能够准确评估痴呆程度。在28例病例中的23例中，STIDA得出的CDR评分与临床医生得出的CDR分数一致，对应未加权kappa值为0.71，加权kappa值为0.81。一种可以直接施用于受试者的大幅简化的简短STIDA能够以0.93的灵敏度和0.77的特异度检测出可能的损害。这些结果表明，简短STIDA为痴呆提供了一种敏感且相当特异的电话筛查方法，而完整的STIDA，包括对知识渊博的知情者的访谈和受试者测试，接近面对面临床访谈的成功率，并通过电话提供可靠且有效的痴呆筛查和分期。
