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重症肌无力胸腺切除术的电生理评估。初步研究结果。

Electrophysiologic evaluations of thymectomy in myasthenia gravis. Preliminary findings.

作者信息

Horowitz S H, Genkins G, Papatestas A E, Kornfeld P

出版信息

Neurology. 1976 Jul;26(7):615-9. doi: 10.1212/wnl.26.7.615.

DOI:10.1212/wnl.26.7.615
PMID:945508
Abstract

Electric testing was performed in 106 myasthenia gravis patients before and after transcervical thymectomy. Twenty-nine were followed for 3 to 24 months. Results were correlated with thymic pathology, duration of disease, age at operation, and follow-up clinical status. Electric improvement was significantly greater in patients without thymic germinal centers or with only rare to occasional germinal centers, in patients operated on within 1 year after onset of symptoms, and in patients under age 30. Electric improvement immediately after thymectomy heralded later clinical improvement in those patients without germinal centers or with rare to occasional germinal centers. Electric-clinical correlations were excellent in patients with longer follow-up. Serial electric testing provides an objective evaluation of the patients' clinical status post-thymectomy.

摘要

对106例重症肌无力患者在经颈胸腺切除术前和术后进行了电测试。29例患者随访了3至24个月。结果与胸腺病理、病程、手术年龄及随访临床状况相关。在无胸腺生发中心或仅有罕见至偶见生发中心的患者、症状出现后1年内接受手术的患者以及30岁以下的患者中,电测试改善情况明显更大。在无生发中心或仅有罕见至偶见生发中心的患者中,胸腺切除术后立即出现的电测试改善预示着后期的临床改善。随访时间较长的患者电测试与临床情况相关性良好。连续电测试为胸腺切除术后患者的临床状况提供了客观评估。

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Electrophysiologic evaluations of thymectomy in myasthenia gravis. Preliminary findings.重症肌无力胸腺切除术的电生理评估。初步研究结果。
Neurology. 1976 Jul;26(7):615-9. doi: 10.1212/wnl.26.7.615.
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