Sawada Y, Asada K, Matsuyama N, Hasegawa S, Sasaki S
Department of Thoracic and Cardiovascular Surgery, Osaka Medical College, Takatsuki, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1997 Dec;45(12):2006-10.
Jehovah's Witness who require operation represent a challenge to the physician because of the patients' refusal to accept blood transfusion. We report an 8-year-old male of Jehovah's Witness who underwent a surgical treatment of infective endocarditis. He was transferred to our hospital because of high fever and heart murmur. Echocardiogram revealed a developing vegetation of aortic cusps and an aneurysmal change of the non-coronary sinus Valsalva. On admission he was complicated by anemia, purulent meningitis and suppurative arthritis of left knee. There were no signs of cardiac failure. Erythropoietin (6000 U thrice weekly) and iron (60 mg daily) were given for 11 weeks prior to surgery, raising the hemoglobin level from 9.2 g/dl to 18.4 g/dl. Aortic valve replacement and plasty of the sinus Valsalva were then performed. Intraoperatively hemoglobin concentration dropped to 10.3 g/dl and it raised to 15 g/dl postoperatively. We also used Cell-Saver to reduce blood loss. The patient made an uncomplicated recovery. Erythropoietin therapy contributed substantially to the successful outcome of this case.
由于拒绝接受输血,需要手术治疗的耶和华见证会信徒给医生带来了挑战。我们报告一例8岁患感染性心内膜炎的耶和华见证会男性患者接受了外科治疗。他因高热和心脏杂音被转诊至我院。超声心动图显示主动脉瓣叶有赘生物形成,无冠窦瓦氏窦呈瘤样改变。入院时,他并发贫血、化脓性脑膜炎和左膝化脓性关节炎。没有心力衰竭的迹象。术前11周给予促红细胞生成素(每周三次,每次6000单位)和铁剂(每日60毫克),血红蛋白水平从9.2克/分升升至18.4克/分升。随后进行了主动脉瓣置换术和瓦氏窦成形术。术中血红蛋白浓度降至10.3克/分升,术后升至15克/分升。我们还使用了血液回收机以减少失血。患者恢复顺利。促红细胞生成素治疗对该病例的成功起到了重要作用。