Sanderson M, Williams M A, White E, Daling J R, Holt V L, Malone K E, Self S G, Moore D E
Department of Epidemiology and Biostatistics, University of South Carolina, Columbia, USA.
Am J Epidemiol. 1998 Jan 15;147(2):136-40. doi: 10.1093/oxfordjournals.aje.a009425.
The authors used data from a population-based case-control study of breast cancer in women aged < or = 44 years (cases, n = 975; controls, n = 866) conducted between 1994 and 1996 in three counties of western Washington state to assess the validity and reliability of reported perinatal factors. For a sample of participants, exposure information from self-administered questionnaires was validated with information from birth certificates (cases, n = 378; controls, n = 283). Detailed information regarding perinatal characteristics of their daughters was also collected from subjects' mothers (case mothers, n = 510; control mothers, n = 436) to assess the reliability of subjects' reporting of these events. Although reporting of birth weight by subjects (cases, r = 0.83; controls, r = 0.80) and their mothers (case mothers, r = 0.89; control mothers, r = 0.84) was highly correlated with the birth certificates, there was differential measurement error by subjects; cases reported birth weight accurately on average, but controls tended to underestimate their birth weight. Agreement between the subject and mother report was excellent for birth weight (cases, r = 0.85; controls, r = 0.87) and good for other perinatal factors, but birth order and maternal diethylstilbestrol use were underreported among cases and reported accurately among controls. Differential measurement error of birth weight by case-control status resulted in biased odds ratios for breast cancer risk.
作者使用了1994年至1996年在华盛顿州西部三个县进行的一项基于人群的44岁及以下女性乳腺癌病例对照研究的数据，以评估所报告围产期因素的有效性和可靠性。对于一部分参与者样本，通过出生证明信息对自我填写问卷中的暴露信息进行了验证（病例组n = 378；对照组n = 283）。还从受试者的母亲那里收集了有关其女儿围产期特征的详细信息（病例组母亲n = 510；对照组母亲n = 436），以评估受试者对这些事件报告的可靠性。尽管受试者（病例组，r = 0.83；对照组，r = 0.80）及其母亲（病例组母亲，r = 0.89；对照组母亲，r = 0.84）报告的出生体重与出生证明高度相关，但受试者存在不同程度的测量误差；病例组平均准确报告了出生体重，但对照组往往低估了他们的出生体重。受试者与母亲报告之间在出生体重方面的一致性非常好（病例组，r = 0.85；对照组，r = 0.87），在其他围产期因素方面一致性良好，但病例组中出生顺序和母亲己烯雌酚使用情况报告不足，而对照组报告准确。出生体重因病例对照状态的不同测量误差导致乳腺癌风险的优势比存在偏差。
