Takahashi S, Murakami T, Narumi Y, Kurachi H, Tsuda K, Kim T, Enomoto T, Tomoda K, Miyake A, Murata Y, Nakamura H
Department of Radiology, Osaka University Medical School, Japan.
Radiology. 1998 Feb;206(2):539-47. doi: 10.1148/radiology.206.2.9457210.
To evaluate the usefulness of T2-weighted fast spin-echo magnetic resonance (MR) imaging with a 512 x 256 matrix for assessment of the preoperative stage of endometrial carcinoma.
Twenty-eight women with histopathologically proved endometrial carcinoma underwent preoperative T2-weighted fast spin-echo, dynamic T1-weighted fast spin-echo, and postcontrast T1-weighted spin-echo MR imaging with a phased-array surface coil. The uterine long-axis planes in each sequence were reviewed at separate sessions by three radiologists blinded to the histopathologic data.
For the diagnosis of myometrial invasion, no statistically significant differences were found among T2-weighted imaging, dynamic imaging, and postcontrast T1-weighted imaging. For the diagnosis of deep myometrial invasion, T2-weighted and dynamic images showed higher specificity than postcontrast T1-weighted images (T2-weighted, 89%; dynamic, 88%; and postcontrast T1-weighted, 80%). For cervical invasion, T2-weighted and dynamic images showed larger areas under receiver operating characteristic curves than did postcontrast T1-weighted images (T2-weighted, 0.78; dynamic, 0.71; and postcontrast T1-weighted, 0.67).
T2-weighted imaging is useful for identifying the stage of endometrial carcinoma.
评估采用512×256矩阵的T2加权快速自旋回波磁共振（MR）成像在评估子宫内膜癌术前分期中的作用。
28例经组织病理学证实为子宫内膜癌的女性患者，术前行T2加权快速自旋回波、动态T1加权快速自旋回波及对比剂增强T1加权自旋回波MR成像，采用相控阵表面线圈。三位对组织病理学数据不知情的放射科医生在不同时间分别查看每个序列中的子宫长轴平面图像。
对于肌层浸润的诊断，T2加权成像、动态成像及对比剂增强T1加权成像之间未发现统计学上的显著差异。对于深层肌层浸润的诊断，T2加权图像和动态图像显示出比对比剂增强T1加权图像更高的特异性（T2加权图像为89%，动态图像为88%，对比剂增强T1加权图像为80%）。对于宫颈浸润，T2加权图像和动态图像在受试者操作特征曲线下的面积比对比剂增强T1加权图像更大（T2加权图像为0.78，动态图像为0.71，对比剂增强T1加权图像为0.67）。
T2加权成像有助于确定子宫内膜癌的分期。
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