Durmaz B, Durmaz R, Sahin K
Department of Clinical Microbiology, Faculty of Medicine, Inönü University, Malatya, Turkey.
J Hosp Infect. 1997 Dec;37(4):325-9. doi: 10.1016/s0195-6701(97)90149-3.
The purposes of this study were to determine the prevalence of Turkish isolates of methicillin-resistant Staphylococcus aureus (MRSA) in nosocomial and community infections and their antibiotic resistant patterns. The oxacillin disk diffusion method for the detection of methicillin resistance and the Kirby-Bauer disk diffusion for antibiotic susceptibility tests were used. A total 383 S. aureus strains were identified from different patients. The prevalence of methicillin resistance among S. aureus strains was 31.3% (120/383). The proportions of MRSA isolated from nosocomial and community infections were 26.4% (46/174) and 35.4% (74/209), respectively. The resistance rates of MRSA to other antibiotics were as follows: 71% resistant to erythromycin, 54% to clindamycin, 52% to gentamicin, 44.5% to trimethoprim-sulfamethoxazole and 36% to ciprofloxacin. No strain resistant to vancomycin was recorded in this study.
本研究的目的是确定土耳其耐甲氧西林金黄色葡萄球菌（MRSA）分离株在医院感染和社区感染中的流行情况及其抗生素耐药模式。采用苯唑西林纸片扩散法检测甲氧西林耐药性，采用 Kirby-Bauer 纸片扩散法进行抗生素敏感性试验。从不同患者中总共鉴定出 383 株金黄色葡萄球菌。金黄色葡萄球菌菌株中甲氧西林耐药率为 31.3%（120/383）。从医院感染和社区感染中分离出的 MRSA 比例分别为 26.4%（46/174）和 35.4%（74/209）。MRSA 对其他抗生素的耐药率如下：对红霉素耐药率为 71%，对克林霉素为 54%，对庆大霉素为 52%，对甲氧苄啶-磺胺甲恶唑为 44.5%，对环丙沙星为 36%。本研究中未记录到对万古霉素耐药的菌株。
