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慢性稳定型心绞痛患者的冠状动脉旁路移植术:适应证与预后(SECOR/SBU)。瑞典心脏病学会、胸放射学会和胸外科协会/瑞典卫生保健技术评估委员会

CABG in chronic stable angina pectoris patients: indications and outcomes (SECOR/SBU). Swedish Societies for Cardiology, Thoracic Radiology and Thoracic surgery/Swedish Council for Technology Assessment in Health Care.

作者信息

Brorsson B, Lindvall B, Bernstein S J, Aberg T

机构信息

Swedish Council on Technology Assessment in Health Care (Statens beredning för medicinsk utvärdering), Stockholm.

出版信息

Eur J Cardiothorac Surg. 1997 Nov;12(5):746-52. doi: 10.1016/s1010-7940(97)00089-4.

Abstract

OBJECTIVE

In order to ascertain the reasons why coronary revascularisation is performed, the appropriateness of these procedures and their outcomes, a national collaborative study encompassing 7 of 8 hospitals performing CABG in Sweden was undertaken. This article presents the indications and outcomes in the largest intervention group, chronic stable angina pectoris treated by first time CABG.

METHODS

A prospective multi-centre study was carried out during a 3.5 month period in each centre. Patients (1039) with chronic stable angina pectoris undergoing first time CABG were enrolled. Patients' quality of life was recorded at the time they underwent angiography and again 6 months post-operatively. Mortality and serious peri-and post-operative complications were recorded. The study was designed and carried out by an independent government agency, the Swedish Council for Technology Assessment in Health Care (SBU) with a project group of representatives for the Swedish Societies for Cardiology, Thoracic Radiology and Thoracic Surgery.

RESULTS

Median age was 66 years. A total of 80% were males. The mortality rates at 30 days and 6 months were 1.0 and 1.9%, respectively. A balloon pump was used for 0.9% of patients and 1.4% of them were on a respirator for more than 24 h. At recruitment, 43.9% of the patients reported having severe angina (CCS II/IV), 70.1% had angina > or = 3 times per week, and 53.1% used sublingual nitrates > or = 3 times per week. The corresponding results at 6 months were 6.7, 10.5 and 3.3%, respectively. Patient satisfaction with operative treatment was high. In comparison with the pre-operative status, quality of life was markedly improved after surgery.

CONCLUSION

This study shows that CABG in chronic stable angina pectoris yields good outcomes with a low mortality and morbidity and a high degree of patient satisfaction and quality of life.

摘要

目的

为了确定进行冠状动脉血运重建的原因、这些手术的合理性及其结果,开展了一项全国性合作研究,涵盖了瑞典8家进行冠状动脉搭桥术(CABG)的医院中的7家。本文介绍了最大干预组(首次CABG治疗慢性稳定型心绞痛)的适应症和结果。

方法

每个中心在3.5个月的时间内进行了一项前瞻性多中心研究。纳入了1039例接受首次CABG的慢性稳定型心绞痛患者。在患者进行血管造影时以及术后6个月再次记录其生活质量。记录死亡率以及严重的围手术期和术后并发症。该研究由一个独立的政府机构瑞典医疗技术评估委员会(SBU)设计并开展,项目组由瑞典心脏病学会、胸放射学会和胸外科学会的代表组成。

结果

中位年龄为66岁。共有80%为男性。30天和6个月时的死亡率分别为1.0%和1.9%。0.9%的患者使用了球囊泵,其中1.4%的患者使用呼吸机超过24小时。在入组时,43.9%的患者报告有严重心绞痛(加拿大心血管学会分级II/IV级),70.1%的患者每周心绞痛发作≥3次,53.1%的患者每周使用舌下硝酸酯类药物≥3次。6个月时的相应结果分别为6.7%、10.5%和3.3%。患者对手术治疗的满意度较高。与术前状态相比,术后生活质量有显著改善。

结论

本研究表明,慢性稳定型心绞痛患者进行CABG可获得良好的结果,死亡率和发病率低,患者满意度和生活质量高。

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