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与正常人群相比,慢性稳定型心绞痛患者在冠状动脉血运重建术前及术后四年的生活质量。

Quality of life of patients with chronic stable angina before and four years after coronary revascularisation compared with a normal population.

作者信息

Brorsson B, Bernstein S J, Brook R H, Werkö L

机构信息

The Swedish Council on Technology Assessment in Health Care, Stockholm, Sweden.

出版信息

Heart. 2002 Feb;87(2):140-5. doi: 10.1136/heart.87.2.140.

Abstract

OBJECTIVE

To assess the impact of coronary revascularisation on the health related quality of life (HRQOL) of patients with chronic stable angina compared with data from "community" norms four years following revascularisation.

DESIGN

Prospective survey and review of medical records.

SETTING

Seven of the eight public Swedish heart centres that performed coronary artery interventions.

SUBJECTS

827 patients aged 55-79 years with chronic stable angina who underwent coronary artery revascularisation in 1994 or 1995 and completed the four year HRQOL survey.

MAIN OUTCOME MEASURES

Five components of the Swedish quality of life survey.

RESULTS

Compared with age and sex adjusted population norms, patients at baseline had significantly lower mean scores on all five functioning and wellbeing scales (p < 0.001). Four years after revascularisation, the mean levels of functioning and wellbeing were similar to those in the normative population (p > 0.05) except for quality of sleep (p < 0.001). The improvements were the same across age groups and for men and women. However, 36% of men and 55% of women were not completely free from angina by four years (p < 0.001). Men without angina after four years had better HRQOL than their community norms (p < 0.001) on all dimensions except quality of sleep (p > 0.05). Women without angina had less pain (p < 0.01) and better general health perception (p < 0.05) but similar physical functioning, quality of sleep, and emotional wellbeing compared with their community counterparts. Both men and women who had suffered at least one anginal attack during the preceding four weeks had significantly worse HRQOL by four years than their community norms (p < 0.01).

CONCLUSIONS

By four years following revascularisation, three fifths of patients with chronic stable angina were free of angina and their HRQOL was the same as or better than that of the general Swedish population. However, fewer than half of all women and two thirds of men who underwent revascularisation were angina-free after four years. Among patients with new or persistent angina, the HRQOL was worse than that in community norms.

摘要

目的

评估冠状动脉血运重建对慢性稳定型心绞痛患者健康相关生活质量(HRQOL)的影响,并与血运重建四年后的“社区”标准数据进行比较。

设计

前瞻性调查及病历回顾。

地点

瑞典八个进行冠状动脉介入治疗的公立心脏中心中的七个。

研究对象

827例年龄在55 - 79岁之间的慢性稳定型心绞痛患者,这些患者于1994年或1995年接受了冠状动脉血运重建,并完成了四年的HRQOL调查。

主要观察指标

瑞典生活质量调查的五个组成部分。

结果

与年龄和性别调整后的人群标准相比,患者在基线时所有五个功能和幸福感量表上的平均得分均显著较低(p < 0.001)。血运重建四年后,除睡眠质量外(p < 0.001),功能和幸福感的平均水平与正常人群相似(p > 0.05)。各年龄组以及男性和女性的改善情况相同。然而,四年后36%的男性和55%的女性仍未完全摆脱心绞痛(p < 0.001)。四年后无心绞痛的男性在除睡眠质量外(p > 0.05)的所有维度上的HRQOL均优于其社区标准(p < 0.001)。无心绞痛的女性疼痛较轻(p < 0.01),总体健康感知较好(p < 0.05),但与社区同龄人相比,身体功能、睡眠质量和情绪幸福感相似。在前四周内至少经历过一次心绞痛发作的男性和女性,四年后的HRQOL均显著低于其社区标准(p < 0.01)。

结论

血运重建四年后,五分之三的慢性稳定型心绞痛患者摆脱了心绞痛,其HRQOL与瑞典普通人群相同或更好。然而,接受血运重建的所有女性中不到一半以及男性中三分之二在四年后无心绞痛。在有新发或持续性心绞痛的患者中,HRQOL低于社区标准。

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