Bloebaum R D, Bachus K N, Jensen J W, Hofmann A A
Bone and Joint Research Laboratory, VA Medical Center, Salt Lake City, UT 84148, USA.
J Arthroplasty. 1997 Dec;12(8):920-9. doi: 10.1016/s0883-5403(97)90162-5.
The objective of this investigation was to conduct a postmortem analysis of 8 porous-coated asymmetric tibial components to measure the extent of radiolucencies and bone ingrowth. With the use of radiographic, electron microscope, and histologic analysis techniques, a quantitative postmortem study of 8 consecutively retrieved porous-coated tibial components was conducted. Time in situ averaged 47+/-36 months. The components were secured with 4 pegs and 2 screws. Autograft bone chips were applied to the resected tibia during implantation. Contact radiographs of an average of 8 3-mm sections from each implant revealed that 73%+/-17% of the porous coating had no apparent radiolucencies present between the host bone and porous coating for the series. Backscattered electron imaging showed that the bone ingrowth averaged 6%+/-2%. Histologic analysis was unable to demonstrate any adverse cellular response. The analysis suggested that this asymmetric implant design is stable and biocompatible and has potential for long-term clinical durability.
本研究的目的是对8个多孔涂层非对称胫骨部件进行尸检分析，以测量透射线程度和骨长入情况。通过使用射线照相、电子显微镜和组织学分析技术，对8个连续取出的多孔涂层胫骨部件进行了定量尸检研究。植入原位的时间平均为47±36个月。这些部件用4个栓子和2个螺钉固定。植入时将自体骨屑应用于切除的胫骨。对每个植入物平均8个3毫米切片的接触式射线照片显示，该系列中73%±17%的多孔涂层在宿主骨和多孔涂层之间没有明显的透射线。背散射电子成像显示骨长入平均为6%±2%。组织学分析未能显示任何不良细胞反应。分析表明，这种非对称植入物设计稳定且具有生物相容性，具有长期临床耐久性的潜力。
