Kawashima O, Hirai T, Kamiyoshihara M, Ishikawa S, Morishita Y
Department of Surgery, National Sanatorium Nishigunma Hospital, 2854 Kanai, Shibukawa, Gunma, 377, Japan.
Oncol Rep. 1998 Jan-Feb;5(1):135-8.
Because of the rarity of its occurrence, there is no established treatment for early stage primary pulmonary lymphoma. We retrospectively examined five patients with early stage primary pulmonary lymphoma to elucidate the optimal treatment for this unusual disease. All patients underwent complete resection with regional lymph node dissection. Lymphatic and blood vessel invasion were pathologically detected in all cases. All four patients with postoperative chemotherapy are alive without recurrence. One patient who did not undergo chemotherapy had an extrapulmonary recurrence 21 months after operation. The combined therapy of complete resection and postoperative chemotherapy may be the treatment of choice for this unusual disease.
由于原发性肺淋巴瘤早期病例罕见,目前尚无既定的治疗方法。我们回顾性研究了5例早期原发性肺淋巴瘤患者,以阐明针对这种罕见疾病的最佳治疗方法。所有患者均接受了根治性切除及区域淋巴结清扫。所有病例在病理检查中均发现有淋巴管及血管侵犯。接受术后化疗的4例患者均存活且无复发。1例未接受化疗的患者术后21个月出现肺外复发。根治性切除联合术后化疗可能是这种罕见疾病的首选治疗方法。