Tulandi T, Watkin K, Tan S L
Royal Victoria Hospital, Department of Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada.
Int J Fertil Womens Med. 1997 Nov-Dec;42(6):436-40.
To evaluate the changes in ovarian volume and the reproductive outcome after laparoscopic treatment of polycystic ovaries (PCOS) in clomiphene-resistant anovulatory women.
A prospective study of women undergoing laparoscopic treatment of polycystic ovaries. Ultrasound examination for three-dimensional (3D) volume determination was performed before and after surgery.
University teaching hospital.
Thirty-four women with polycystic ovarian syndrome who failed to ovulate with clomiphene citrate and who subsequently underwent laparoscopic ovarian drilling.
Laparoscopic ovarian drilling and three-dimensional ultrasound examination.
Cumulative probability of conception and changes in ovarian volume.
Ovulation rate after the procedure was 30/34 (88.2%). Using Life Table Analysis, the cumulative probability of conception at 12 months follow-up was 70% (median, 8.1 months). The preoperative ovarian volume was 12.2 +/- 1.8 cm3 and 1 week after surgery it was 13.6 +/- 1.5 cm3. The ovarian volume 3 weeks after surgery, 6.9 +/- 1.3 cm3, was significantly smaller than that before surgery.
Laparoscopic treatment of polycystic ovaries in women with clomiphene-resistant PCOS is associated with an ovulation rate of 88.2% and a cumulative pregnancy rate of 70% at 12 months. It appears also that laparoscopic ovarian drilling may result in a transient increase, with a subsequent significant reduction, in ovarian volume.
评估克罗米芬抵抗性无排卵妇女多囊卵巢（PCOS）腹腔镜治疗后卵巢体积变化及生殖结局。
对接受多囊卵巢腹腔镜治疗的妇女进行前瞻性研究。手术前后进行三维（3D）体积测定的超声检查。
大学教学医院。
34例多囊卵巢综合征妇女，她们使用枸橼酸克罗米芬未能排卵，随后接受了腹腔镜卵巢打孔术。
腹腔镜卵巢打孔术和三维超声检查。
受孕累积概率和卵巢体积变化。
术后排卵率为30/34（88.2%）。采用寿命表分析，随访12个月时受孕累积概率为70%（中位数为8.1个月）。术前卵巢体积为12.2±1.8 cm³，术后1周为13.6±1.5 cm³。术后3周卵巢体积为6.9±1.3 cm³，明显小于术前。
克罗米芬抵抗性PCOS妇女多囊卵巢的腹腔镜治疗排卵率为88.2%，12个月时累积妊娠率为70%。腹腔镜卵巢打孔术似乎也可能导致卵巢体积短暂增加，随后显著减小。
