正亮氨酸对顶头孢霉中菌丝体断裂的影响。
Effect of norleucine on mycelial fragmentation in Cephalosporium acremonium.
作者信息
Drew S W, Winstanley D J, Demain A L
出版信息
Appl Environ Microbiol. 1976 Jan;31(1):143-5. doi: 10.1128/aem.31.1.143-145.1976.
Abstract
DL-Norleucine, which is known to replace methionine for stimulation of cephalosporin C formation, also mimics methionine's effect on arthrospore formation. Thus, hyphal fragmentation, like antibiotic biosynthesis, is divorced from a sulfur donation role.
摘要
已知可替代甲硫氨酸以刺激头孢菌素C形成的DL-正亮氨酸，也能模拟甲硫氨酸对节孢子形成的作用。因此，菌丝断裂，如同抗生素生物合成一样，与硫供体作用无关。
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本文引用的文献
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Effect of Methionine and Sulfate on the Metabolism of Cephalosporium acremonium.蛋氨酸和硫酸盐对顶头孢霉代谢的影响。
Appl Microbiol. 1968 Dec;16(12):1913-8. doi: 10.1128/am.16.12.1913-1918.1968.
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Effect of methionine, norleucine, and lysine derivatives on cephalosporin C formation in chemically defined media.蛋氨酸、正亮氨酸和赖氨酸衍生物对化学限定培养基中头孢菌素C形成的影响。
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Biosynthesis of penicillin N and cephalosporin C. Antibiotic production and other features of the metabolism of Cephalosporium sp.青霉素N和头孢菌素C的生物合成。头孢霉属的抗生素生产及代谢的其他特征
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Role of methionine in cephalosporin synthesis.蛋氨酸在头孢菌素合成中的作用。
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Sulfatase regulation and antibiotic synthesis in Cephalosporium acremonium.
Can J Microbiol. 1969 Feb;15(2):175-81. doi: 10.1139/m69-029.
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Antibiotic synthesis and morphological differentiation of Cephalosporium acremonium.顶头孢霉的抗生素合成与形态分化
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