Benacerraf B R, Bromley B
Department of Obstetrics & Gynecology, Massachusetts General Hospital, Harvard Medical School, Boston, USA.
J Clin Ultrasound. 1998 Feb;26(2):69-71. doi: 10.1002/(sici)1097-0096(199802)26:2<69::aid-jcu3>3.0.co;2-g.
We evaluated the outcome of fetuses with prenatally diagnosed undescended testes at 35 weeks or more of gestation.
We identified the fetuses in our database in whom undescended testes were identified sonographically in the last month of pregnancy and for whom outcome information could be obtained. Associated sonographic abnormalities were tabulated from the original reports. Outcomes were obtained through reviews of the pediatric medical records and pathology reports.
Six fetuses in 5 patients (1 had twins) were identified as having an empty scrotum at 35 weeks or later. In 3 fetuses, this finding was the only prenatal sonographic abnormality. One of these fetuses had isolated undescended testes at birth; the twins were found at birth to be females with congenital adrenal hyperplasia and severe masculinization of the genitals. The other 3 fetuses had other malformations seen prenatally, including omphalocele and macroglossia (Beckwith-Wiedemann syndrome), a left diaphragmatic hernia, and multiple congenital abnormalities.
Although the finding of undescended testes in late gestation may be noted in an otherwise normal fetus, it may also be associated with a potential risk for perinatal problems ranging from severe multiple congenital abnormalities to incorrect sex assignment due to masculinization of female genitalia.
我们评估了妊娠35周及以上产前诊断为隐睾的胎儿的结局。
我们在数据库中识别出那些在妊娠最后一个月经超声检查发现隐睾且能获取结局信息的胎儿。从原始报告中列出相关的超声异常情况。通过查阅儿科病历和病理报告获取结局信息。
5例患者中的6名胎儿（1例为双胞胎）在35周及以后被确定阴囊内无睾丸。在3例胎儿中，这一发现是唯一的产前超声异常。其中1例胎儿出生时为单纯性隐睾；双胞胎出生时被发现为女性，患有先天性肾上腺皮质增生症且生殖器严重男性化。另外3例胎儿产前还存在其他畸形，包括脐膨出和巨舌（贝克威思-维德曼综合征）、左侧膈疝以及多种先天性异常。
尽管妊娠晚期发现隐睾可能出现在其他方面正常的胎儿中，但它也可能与围产期问题的潜在风险相关，这些问题从严重的多种先天性异常到因女性生殖器男性化导致的性别分配错误不等。
