Glanc Phyllis, Umranikar Shalini, Koff David, Tomlinson George, Chitayat David
Department of Medical Imaging, Sunnybrook Health Sciences Centre, Women's College Hospital, University of Toronto, Toronto, ON M5S 1B2, Canada.
J Ultrasound Med. 2007 May;26(5):563-9; quiz 570-1. doi: 10.7863/jum.2007.26.5.563.
The purpose of this study was to determine the feasibility and reliability of fetal sex assignment by prenatal sonography of the pelvic organs in the second and third trimesters.
A prospective study, on an axial pelvic image with the umbilical arteries in cross section at the midpoint of the bladder, measured the distance between the posterior wall of the bladder and the anterior wall of the rectum. The bladder interface was scored as concave, flat, or convex. Endometrium visualization was recorded. A video loop of the pelvis was obtained. Each case was read by a second reader aware of only the gestational age.
The study population included 205 fetuses. The primary reader was 98.8% accurate in identifying true female fetuses and 100% accurate in identifying true male fetuses. The intraclass correlation coefficient for axial measurement was 0.99. Video loop analysis achieved 96% inter-reader concordance. In the second trimester, measurements in 100% of male fetuses were less than 3.3 mm, and those in 94% of female fetuses were greater than 3.3 mm. In the third trimester, measurements in 96% of male fetuses were less than 4.7 mm, and those in 100% of female fetuses were greater than 4.7 mm. Ninety-eight percent of all fetuses with concave interfaces were female. The endometrium was visualized in 74%. The additional time per examination was less than 5 minutes in 87.7%.
Internal pelvic fetal sex assignment is a reliable additional method for fetal sex determination. A numerical discriminatory level can be used to distinguish between male and female internal genitalia. Larger numbers will be required to further refine these values.
本研究旨在确定孕中期和孕晚期通过盆腔器官产前超声检查进行胎儿性别判定的可行性和可靠性。
一项前瞻性研究,在膀胱中点处脐动脉呈横截面的盆腔轴位图像上,测量膀胱后壁与直肠前壁之间的距离。膀胱界面分为凹形、扁平形或凸形。记录子宫内膜的可视化情况。获取盆腔的视频环。每个病例由仅知晓孕周的第二位阅片者进行阅片。
研究人群包括205例胎儿。主阅片者在识别真女性胎儿方面的准确率为98.8%,在识别真男性胎儿方面的准确率为100%。轴向测量的组内相关系数为0.99。视频环分析的阅片者间一致性达到96%。在孕中期,100%的男性胎儿测量值小于3.3毫米,94%的女性胎儿测量值大于3.3毫米。在孕晚期,96%的男性胎儿测量值小于4.7毫米,100%的女性胎儿测量值大于4.7毫米。所有界面为凹形的胎儿中有98%为女性。74%的病例可观察到子宫内膜。87.7%的检查每次额外用时少于5分钟。
盆腔内胎儿性别判定是一种可靠的胎儿性别确定辅助方法。可以使用数值判别水平来区分男性和女性内生殖器。需要更多病例进一步完善这些数值。