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[枪伤骨折愈合中的再生骨组织发生(细胞间质中胶原纤维的光学偏振分析)]

[Regeneration osteohistogenesis in the healing of gunshot fractures (an optical polarization analysis of the collagen fibers in the intercellular substance)].

作者信息

Gololobov V G

出版信息

Morfologiia. 1997;112(5):22-5.

PMID:9460673
Abstract

Bone tissue intercellular substance was studied in healing of a tibial gunshot fracture in dog. The method of scanning polarization microscopy was used with cytospectrophotometer signal registration and the following three-dimensional computer reconstruction of indexes of the process which was monitored from days 15 to 120 of the experiment. By the end of the experiment optic anisotropy indexes of collagen fibres from proximal and distal bone fragments were 96 and 80 respectively as related to intact bone. Character of scanogrammes and increasing values of anisotropy indexes of fibrous component of the regenerate intercellular substance indicate changing and normalizing fibrillar architectonics of newly formed bone tissue on the site of preceding fracture and serve as one of criteria for regenerative osteogenesis phases.

摘要

对犬胫骨枪伤骨折愈合过程中的骨组织细胞间质进行了研究。采用扫描偏振显微镜法,通过细胞分光光度计记录信号,并对实验第15天至120天监测的过程指标进行三维计算机重建。实验结束时,近端和远端骨碎片中胶原纤维的光学各向异性指数与完整骨相比分别为96和80。扫描图的特征以及再生细胞间质纤维成分各向异性指数的增加表明,先前骨折部位新形成骨组织的纤维结构在发生变化并趋于正常化,这是再生性骨生成阶段的标准之一。

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