Stewart R D, Hake C L
JAMA. 1976 Jan 26;235(4):398-401.
The in-home use of paint removers containing methylene chloride results in the absorption of this solvent, which is metabolized to carbon monoxide. Exposure for two to three hours can result in the elevation of carboxyhemoglobin (COHb) to levels that stress the cardiovascular system. The metabolic formation of COHb continues following the paint-remover exposure, doubling the duration of the cardiovascular stress produced by a comparable COHb level after exposure to CO. Patients with diseased cardiovascular systems may not be able to tolerate this unexpected stress.
在家中使用含有二氯甲烷的脱漆剂会导致这种溶剂被吸收,该溶剂会代谢为一氧化碳。接触两到三个小时会导致碳氧血红蛋白(COHb)水平升高,从而给心血管系统造成压力。接触脱漆剂后,COHb的代谢形成仍会继续,使接触一氧化碳后由相当的COHb水平产生的心血管压力持续时间加倍。患有心血管疾病的患者可能无法承受这种意外的压力。