Verschoor E J, Warren K S, Niphuis H, Swan R A, Heeney J L
Department of Virology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
J Gen Virol. 1998 Jan;79 ( Pt 1):51-5. doi: 10.1099/0022-1317-79-1-51.
In a recent serological survey among 143 ex-captive orang-utans two individuals were found that reacted positive in an ELISA detecting antibodies which cross-react with human T-lymphotropic virus type I (HTLV-I) antigens. Infection of both animals with an HTLV-I or simian T-lymphotropic virus (STLV)-like virus was confirmed by Western blot analysis. A third wild-caught animal, which was not part of the original serological survey, was also found to be infected with an HTLV-related virus in a diagnostic PCR assay and Western blot assay. Nucleotide sequence analysis of the 709 bp PCR fragment from the tax/rex region of the HTLV/STLV genome confirmed infection of orang-utans with an STLV similar to but clearly distinct from other Asian STLVs.
在最近对143只曾被圈养的红毛猩猩进行的血清学调查中，发现有两只个体在检测与人类I型嗜T淋巴细胞病毒（HTLV-I）抗原发生交叉反应抗体的ELISA检测中呈阳性。通过蛋白质印迹分析证实这两只动物均感染了HTLV-I或类猿猴嗜T淋巴细胞病毒（STLV）。在一项诊断性PCR检测和蛋白质印迹检测中，还发现第三只野生捕获的动物（它并非最初血清学调查的对象）感染了一种与HTLV相关的病毒。对来自HTLV/STLV基因组tax/rex区域的709 bp PCR片段进行的核苷酸序列分析证实，红毛猩猩感染了一种与其他亚洲STLV相似但明显不同的STLV。
