Amato Neto V, Carignani F L, Matsubara L, Braz L M
Laboratório de Investigação Médica-Parasitologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, SP, Brasil.
Rev Soc Bras Med Trop. 1997 Nov-Dec;30(6):481-4. doi: 10.1590/s0037-86821997000600007.
Strongyloides venezuelensis experimental infection in rats was treated by two different oral preparations of ivermectin, 0.2 mg/kg. One was a human formula used by WHO in the treatment of onchocerciasis; the other was a veterinary preparation. Adult worms and larvae were evaluated. The human formulation cleared both forms in 59.3% (adult worms) and 73.0% (larvae), whereas the veterinary one cleared 98.0% and 84.2%, respectively. The antilarval action is very useful when treating systemic strongyloidiasis.
用两种不同的伊维菌素口服制剂（0.2毫克/千克）对感染委内瑞拉类圆线虫的大鼠进行实验性治疗。一种是世界卫生组织用于治疗盘尾丝虫病的人用配方；另一种是兽用制剂。对成虫和幼虫进行了评估。人用配方清除成虫的比例为59.3%，清除幼虫的比例为73.0%，而兽用制剂清除成虫和幼虫的比例分别为98.0%和84.2%。在治疗全身性类圆线虫病时，抗幼虫作用非常有用。
