Jenkins M A, Langlais P J, Delis D, Cohen R
Department of Neurology Research, Department of Veterans' Affairs Medical Center, San Diego, USA.
Am J Psychiatry. 1998 Feb;155(2):278-9. doi: 10.1176/ajp.155.2.278.
Studies have shown memory deficits among combat veterans with posttraumatic stress disorder (PTSD); however, high rates of comorbid conditions, including alcoholism, make it difficult to definitively associate these findings with the PTSD diagnosis. In this study the authors examined memory functioning among rape survivors without alcoholism or substance abuse but with PTSD.
Rape victims with (N = 15) and without (N = 16) PTSD were compared to age- and education-matched nontraumatized comparison subjects (N = 16) on measures of learning and memory.
The subjects with PTSD performed significantly worse than the other groups on delayed free recall. The deficits were ameliorated by cueing and recognition testing.
Recall deficits in noncombat PTSD patients strengthen the theory that memory deficits are associated with the PTSD diagnosis. The deficits were mild and were not attributable to comorbid depression, anxiety, or substance abuse.
研究表明,患有创伤后应激障碍(PTSD)的退伍军人存在记忆缺陷;然而,包括酗酒在内的高共病率使得难以将这些发现明确地与PTSD诊断联系起来。在本研究中,作者考察了无酗酒或药物滥用但患有PTSD的强奸幸存者的记忆功能。
将患有PTSD(N = 15)和未患有PTSD(N = 16)的强奸受害者与年龄和教育程度相匹配的未受创伤的对照受试者(N = 16)在学习和记忆测量方面进行比较。
患有PTSD的受试者在延迟自由回忆方面的表现明显比其他组差。通过线索提示和识别测试,这些缺陷得到了改善。
非战斗PTSD患者的回忆缺陷强化了记忆缺陷与PTSD诊断相关的理论。这些缺陷较轻,并非由共病的抑郁、焦虑或药物滥用所致。