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[一例发生极度囊性变的纵隔精原细胞瘤]

[A case of mediastinal seminoma undergoing extremely cystic degeneration].

作者信息

Kataoka K, Seno N

机构信息

Department of Respiratory Surgery, Hirosima City Hospital.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1997 Oct;35(10):1108-12.

PMID:9465624
Abstract

A-25-year-old male had an abnormal shadow on chest X-ray. CT and MRI films revealed a cystic lesion, with irregular nodules in the right anterior mediastinum. A cystic teratoma was suggested. Antero-axillary thoracotomy revealed a cystic lesion originating from the right lobe of the thymus. The lesion was extirpated, along with the right lobe of the thymus. The cystic part of the lesion, filled with brown fluid, was occupied by several masses originating from the wall of the tumor. Pathologically, the lesion was diagnosed as a seminoma undergoing cystic degeneration. The patient was given post-operative irradiation of 20Gy. No apparent recurrence has been detected 33 months after surgery. Mediastinal seminomas generally occur as a solid tumor consisting of stroma and tumor cells. However, this case report suggests that mediastinal seminomas may undergo extremely cystic degeneration.

摘要

一名25岁男性胸部X线检查发现异常阴影。CT和MRI片子显示右前纵隔有一个囊性病变,伴有不规则结节。考虑为囊性畸胎瘤。经腋下胸廓切开术发现一个起源于胸腺右叶的囊性病变。连同胸腺右叶一起切除了该病变。病变的囊性部分充满褐色液体,被几个起源于肿瘤壁的肿块占据。病理检查诊断该病变为正在发生囊性退变的精原细胞瘤。患者术后接受了20Gy的放疗。术后33个月未发现明显复发。纵隔精原细胞瘤通常表现为实体瘤,由基质和肿瘤细胞组成。然而,本病例报告提示纵隔精原细胞瘤可能会发生极其严重的囊性退变。

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