Tanaka N, Kimura H, Morishima T
Department of Pediatrics, Nagoya University School of Medicine.
Nihon Rinsho. 1998 Jan;56(1):167-72.
We described the clinical feature of cytomegalovirus(CMV) infection, its epidemiology, and prognosis of congenital CMV infection. Then, the anti-viral treatment with the ganciclovir against the congenital CMV infection was discussed. We showed that the presence of CMV-DNA in the plasma was useful to determine the indication of the therapy. We also showed our case of chronic active Epstein-Barr virus infection to introduce the adoptive immune therapy as a new strategy for the treatment of severe virus infections. Lastly, application of this therapy for the CMV infection in overseas and its future prospect were described.
我们描述了巨细胞病毒（CMV）感染的临床特征、流行病学以及先天性CMV感染的预后。然后，讨论了用更昔洛韦治疗先天性CMV感染的抗病毒治疗方法。我们表明，血浆中CMV-DNA的存在有助于确定治疗指征。我们还展示了我们慢性活动性EB病毒感染的病例，以介绍过继性免疫疗法作为治疗严重病毒感染的一种新策略。最后，描述了这种疗法在海外对CMV感染的应用及其未来前景。
