Ruzal-Shapiro C
Department of Radiology, Columbia University, College of Physicians and Surgeons, New York, New York, USA.
Radiol Clin North Am. 1998 Jan;36(1):143-61. doi: 10.1016/s0033-8389(05)70011-7.
A single gene defect in cystic fibrosis results in a spectrum of clinical presentations. Though expression is variable, the radiographic appearance reflects the underlying pathophysiology. Abnormalities of the small airways result in air-trapping; bronchiectasis and mucus plugging reflect large airway disease. These radiographic findings can be assessed and followed using varying scoring systems.
囊性纤维化中的单个基因缺陷会导致一系列临床表现。尽管表达存在差异，但影像学表现反映了潜在的病理生理学。小气道异常导致气体潴留；支气管扩张和黏液阻塞反映大气道疾病。这些影像学表现可以使用不同的评分系统进行评估和随访。
