Ter Bruggen J P, van der Meché F G, de Jager A E, Polman C H
Department of Neurology, University Hospital Utrecht, The Netherlands.
Muscle Nerve. 1998 Feb;21(2):239-42. doi: 10.1002/(sici)1097-4598(199802)21:2<239::aid-mus13>3.0.co;2-x.
We delineated the place of cranial nerve variants within the concept of clinically defined Guillain-Barre syndrome (GBS). In the ophthalmoplegic variant (n = 7) the oculomotor nerves were early involved. In a lower cranial nerve variant (n = 9) the cranial nerves IX, X, and XI were early involved. During progression considerable overlap occurred between these two variants, but also with the classically ascending variant of clinically defined GBS. These findings indicate common immune mechanisms in all GBS variants.
我们在临床定义的吉兰-巴雷综合征（GBS）概念中明确了颅神经变异的情况。在眼肌麻痹型变异（n = 7）中，动眼神经早期受累。在低位颅神经变异（n = 9）中，颅神经IX、X和XI早期受累。在疾病进展过程中，这两种变异之间以及与临床定义的GBS经典上升型之间均出现了相当程度的重叠。这些发现表明所有GBS变异中存在共同的免疫机制。
