Henze M, Hittel J P, Elser H
Abteilung für Nuklearmedizin der Radiologischen Universitätsklinik Heidelberg, Deutschland.
Nuklearmedizin. 1998 Jan;37(1):45-9.
Case report of a 42 year old female, who received 14th-20th year of life six radioiodine therapies with altogether 19.2 GBq131I because of a papillary thyroid carcinoma. 17 years after the last therapy, she developed a histologically proven chronic radiogenic sialadenitis of the left submandibular gland. Further four years later, the right submandibular gland has been extirpated because of a mucoepidermoid carcinoma with infiltration of a regionary lymphatic node. Review of the previous published secondary-malignancies of the salivary glands after high-dose radioiodine therapies.
一名42岁女性的病例报告,该女性在14至20岁时因乳头状甲状腺癌接受了6次放射性碘治疗,总共使用了19.2GBq的131I。在最后一次治疗17年后,她患上了经组织学证实的左下颌下腺慢性放射性涎腺炎。又过了四年,右侧下颌下腺因黏液表皮样癌伴区域淋巴结浸润而被切除。回顾先前发表的关于高剂量放射性碘治疗后唾液腺继发性恶性肿瘤的文献。