直肠吸引活检在婴儿先天性巨结肠症诊断中的应用
Rectal suction biopsy in the diagnosis of Hirschsprung disease in infants.
作者信息
Yunis E J, Dibbins A W, Sherman F E
出版信息
Arch Pathol Lab Med. 1976 Jun;100(6):329-33.
PMID:946762
Abstract
Our experience with 47 rectal suction biopsies performed in infants up to six months of age indicates that this is a simple and effective method for the exclusion of Hirschsprung disease. It requires the recognition of immature ganglion cells in neural units as equivalent to mature ganglion cells. Absence of these immature neural units in an adequate sample is highly suggestive of Hirschsprung disease.
摘要
我们对6个月龄以内婴儿进行47次直肠吸引活检的经验表明，这是一种排除先天性巨结肠病的简单而有效的方法。它需要认识到神经单元中未成熟神经节细胞与成熟神经节细胞等效。在足够的样本中缺乏这些未成熟神经单元高度提示先天性巨结肠病。
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