Clyde H R, Walsh P C, English R W
Fertil Steril. 1976 Jun;27(6):662-6.
Little attention has been given the existence of male infertility in hyperthyroidism and the mechanisms adversely affecting spermatogenesis therein. The chance presentation of three young thyrotoxic men within a short period of time allowed us to document the common findings in all three of reversibly impaired semen quality. The unexpected finding of elevated testosterone and gonadotropin levels in each case, with return of these values to normal on attaining euthyroidism, and the finding of maturation arrest in one patient prior to treatment of his thyrotoxicosis, allow some considerations of the altered physiology and spermatogenic defect and suggest a need for further attention to this disorder.
甲状腺功能亢进症中男性不育的存在及其对精子发生产生不利影响的机制一直未得到足够关注。在短时间内偶然出现的三名年轻甲状腺毒症男性患者，使我们能够记录到他们三人精液质量均出现可逆性损害的共同表现。在每个病例中意外发现睾酮和促性腺激素水平升高，而在甲状腺功能恢复正常后这些值又恢复正常，并且在一名患者甲状腺毒症治疗前发现了成熟停滞，这促使我们对生理改变和生精缺陷进行一些思考，并表明需要进一步关注这种疾病。
