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在降胸段和胸腹主动脉手术中采用深度低温以保护脊髓。

Profound hypothermia for spinal cord protection in operations on the descending thoracic and thoracoabdominal aorta.

作者信息

Rokkas C K, Kouchoukos N T

机构信息

Heart Center, Missouri Baptist Medical Center, St Louis, USA.

出版信息

Semin Thorac Cardiovasc Surg. 1998 Jan;10(1):57-60. doi: 10.1016/s1043-0679(98)70019-x.

Abstract

Elective hypothermic cardiopulmonary bypass with or without circulatory arrest has been used successfully for the treatment of complex aneurysms of the descending thoracic and thoracoabdominal aorta. Hypothermia has a protective effect on spinal cord function, and its use has been associated with a low incidence of paraplegia in traditionally high-risk patients. In our series, 96 consecutive patients underwent resection and graft replacement of diseased aortic segments of the distal aortic arch, the descending thoracic aorta, or the thoracoabdominal aorta. Thirty-day mortality was 7.3%, and the incidence of spinal cord ischemic injury was 3.4%. Our experience with hypothermic cardiopulmonary bypass and circulatory arrest confirms the safety and efficacy of the technique for operations on the descending thoracic and thoracoabdominal aorta.

摘要

选择性低温体外循环伴或不伴循环停止已成功用于治疗降主动脉和胸腹主动脉的复杂动脉瘤。低温对脊髓功能有保护作用,在传统高危患者中使用低温与截瘫发生率低相关。在我们的系列研究中,96例连续患者接受了远端主动脉弓、降主动脉或胸腹主动脉病变主动脉段的切除和移植置换术。30天死亡率为7.3%,脊髓缺血性损伤发生率为3.4%。我们在低温体外循环和循环停止方面的经验证实了该技术用于降主动脉和胸腹主动脉手术的安全性和有效性。

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