Cambria R P, Davison J K
The Division of Vascular Surgery, Massachusetts General Hospital, Boston 02114, USA.
Semin Thorac Cardiovasc Surg. 1998 Jan;10(1):61-5. doi: 10.1016/s1043-0679(98)70020-6.
A technique for regional hypothermic protection of spinal cord with epidural cooling during thoracoabdominal aneurysm (TAA) repair has been applied in over 100 patients. Elevation of cerebrospinal fluid pressure during the infusion is the principle technical limitation of the technique. When compared to institutional historic controls, patients treated with epidural cooling had a significant reduction in spinal cord ischemic complications. In patients treated for elective Types I, II, III TAA with epidural cooling, spinal cord complications have been reduced to the 3% range.
一种在胸腹主动脉瘤(TAA)修复术中通过硬膜外冷却对脊髓进行局部低温保护的技术已应用于100多名患者。输注过程中脑脊液压力升高是该技术的主要技术限制。与机构历史对照相比,接受硬膜外冷却治疗的患者脊髓缺血并发症显著减少。在接受择期I型、II型、III型TAA硬膜外冷却治疗的患者中,脊髓并发症已降至3%左右。