Lioy P J, Yiin L M, Adgate J, Weisel C, Rhoads G G
Environmental and Occupational Health Sciences Institute, UMDNJ-Robert Wood Johnson Medical School, Piscataway 08855, USA.
J Expo Anal Environ Epidemiol. 1998 Jan-Mar;8(1):17-35.
The changes in dust loading, lead loading and lead concentration, determined from vacuum samples and wipe samples collected during the Childhood Lead Exposure Assessment and Reduction Study (CLEARS) were analyzed to determine the efficacy of the cleaning protocol in homes of children found to have moderate lead poisoning, e.g. levels between 10-20 micrograms/dL. The samples were collected at least twice, and in 65 homes three times, during the course of a year long intervention in homes where half were randomized into a group which received a standardized Lead Intervention program for lead reduction, and the other homes only received an Accident Intervention program. The homes with lead burdened children were located in Hudson County, New Jersey (primarily in Jersey City), and were referred to the CLEARS by a number of private and public sources. Each home had wipe sampling conducted with the LWW Sampler (patented), and vacuum sampling was completed using a device described by Wang et al. in Applied Occupational and Environmental Hygiene. The results were compared in two ways: (1) between the two intervention groups, and (2) over the time course of the intervention period. When compared to the values seen in the first visit vacuum sampling results showed statistically significant decreases in lead loading and dust loading by the third sampling visit for the Lead Intervention homes. Substantial reductions in lead loading and dust loading were also seen when the Lead Intervention values were compared to values obtained in the Accident Intervention homes over the course of the year long intervention. The wipe sampling results for the 65 homes with three visits found no significant reductions in dust loading and lead loading among any of the room surfaces sampled in the Accident Intervention homes. There were 75% and 50% reductions observed on the window sills and on the bedroom floors of the homes which participated in the Lead Intervention. The levels in the living room and the kitchen showed very little change in loadings. This appeared to be due to the fact these rooms were near a background or baseline value of 0.3 g/cm2 and 0.12 mg/cm2 for dust loading and lead, respectively. This was substantiated by the window sills and bedroom wipe sampling results since each surface approached these values by the third visit. Significant reductions in lead concentrations found in the wipe samples from the intervention homes appeared to be related to the absence of historically active sources of lead in these homes, rather than elimination of current sources. The results of the micro-environmental sampling program in CLEARS indicated that a year long cleaning protocol can significantly decrease lead levels in rugs and on other exposed surfaces. This will reduce the potential for exposure to lead among the occupants, especially children, that come in contact with such surfaces.
在儿童铅暴露评估与降低研究(CLEARS)期间,对通过真空采样和擦拭采样测定的粉尘负荷、铅负荷及铅浓度变化进行了分析,以确定针对家中被发现患有中度铅中毒(例如血铅水平在10 - 20微克/分升之间)儿童的清洁方案的效果。在为期一年的干预过程中,这些样本至少采集了两次,65户家庭采集了三次,其中一半家庭被随机分为一组,接受标准化的铅减排干预计划,而其他家庭仅接受事故干预计划。有铅负荷儿童的家庭位于新泽西州哈德逊县(主要在泽西城),由多个私人和公共来源转介至CLEARS。每户家庭都使用LWW采样器(专利产品)进行擦拭采样,并使用Wang等人在《应用职业与环境卫生学》中描述的设备完成真空采样。结果通过两种方式进行比较:(1)两个干预组之间;(2)在干预期的时间进程中。与首次访视时的值相比,铅干预家庭在第三次采样访视时,真空采样结果显示铅负荷和粉尘负荷有统计学上的显著下降。在为期一年的干预过程中,将铅干预组的值与事故干预家庭获得的值进行比较时,也发现铅负荷和粉尘负荷有大幅下降。对65户进行了三次访视的家庭的擦拭采样结果显示,事故干预家庭所采样的任何房间表面的粉尘负荷和铅负荷均未显著降低。参与铅干预的家庭的窗台和卧室地板上分别观察到有75%和50%的降幅。客厅和厨房的负荷变化很小。这似乎是因为这些房间的粉尘负荷和铅的背景或基线值分别接近0.3克/平方厘米和0.12毫克/平方厘米。窗台和卧室擦拭采样结果证实了这一点,因为到第三次访视时每个表面都接近这些值。在干预家庭的擦拭样本中发现的铅浓度显著降低似乎与这些家庭中历史上活跃的铅源不存在有关,而不是与当前铅源的消除有关。CLEARS中的微环境采样计划结果表明,为期一年的清洁方案可显著降低地毯和其他暴露表面的铅水平。这将降低居住者尤其是与这些表面接触的儿童接触铅的可能性。