Kemp M, Westh H, Scheibel J H
Klinisk mikrobiologisk afdeling, H:S Rigshospitalet.
Ugeskr Laeger. 1998 Jan 26;160(5):622-5.
The occurrence of penicillin resistance in clinical isolates of pneumococci was investigated in two clinical microbiological laboratories in Copenhagen, Denmark. One of the laboratories predominantly received samples from patients with frequent use of antibiotics mainly because of chronic lung diseases. In this laboratory, 6.3% of 245 isolates of pneumococci had intermediate resistance to penicillin. In the other laboratory, which received samples from a number of hospitals and general practice, only 1.3% of isolates of pneumococci had reduced sensitivity to penicillin. Penicillin-resistant pneumococci are rare in Denmark, but are more prevalent in patients who frequently use antibiotics.
丹麦哥本哈根的两个临床微生物实验室对肺炎球菌临床分离株中的青霉素耐药性出现情况进行了调查。其中一个实验室主要接收来自频繁使用抗生素的患者的样本,主要原因是慢性肺部疾病。在该实验室,245株肺炎球菌分离株中有6.3%对青霉素具有中度耐药性。在另一个从多家医院和全科诊所接收样本的实验室中,只有1.3%的肺炎球菌分离株对青霉素敏感性降低。耐青霉素肺炎球菌在丹麦很少见,但在频繁使用抗生素的患者中更为普遍。