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生物制药参数在药物研发中的作用(作者译)

[The role of biopharmaceutical parameters in drug development (author's transl)].

作者信息

Thoma K

出版信息

Arzneimittelforschung. 1976;26(1A):121-9.

PMID:947191
Abstract

The biopharmaceutical factors, which influence the interaction between dosage form and drug activity, extend from the mode of application, through chemical and physical properties of the active constituent, to the final product, including the excipients and manufacturing processes involved. In recent years, important strides have been made in this field, which improve drug safety. This has consequently influenced and enlarged the present scope of pharmaceutical technology drug research.

摘要

生物制药因素影响剂型与药物活性之间的相互作用,其范围从给药方式,到活性成分的化学和物理性质,再到最终产品,包括所涉及的辅料和制造工艺。近年来,该领域取得了重要进展,提高了药物安全性。这相应地影响并扩大了当前药物技术药物研究的范围。

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