Chattar-Cora D, Onime G D, Coppa G F, Valentine I S, Rivera L
Department of Surgery, Morristown Memorial Hospital, New Jersey, USA.
J Natl Med Assoc. 1998 Jan;90(1):19-24.
This study was undertaken to examine the regional distribution of colorectal cancer, the age of presentation for different subsite locations of the disease and whether there is any intersex difference in frequency of the disease, in New York City Hispanics. The charts of Hispanic patients on file with the tumor registry at Bellevue Hospital Center in New York City from 1976 to 1995 were reviewed. Demographic and pathologic data including patient age and cancer location were analyzed. Lesions of the distal colon and rectum accounted for more than 70%, while right-sided lesions were found in 20.7% of patients. The male to female ratio was 47.6% to 52.4%. The overall mean age of patients was 60.4 years. Proximal lesions presented at a later age than distal lesions, 63.2 years for the right colon and 58.5 years for the rectum; this difference in ages was significant. These results suggest that Hispanic-American patients with colorectal cancer appear to be presenting at an earlier age than the general American population. Further study is needed to determine whether Hispanic women are presenting with a higher frequency of colorectal cancer than their male counterparts and whether Hispanic patients are presenting at an earlier age than the general population with colorectal malignancies and why.
本研究旨在调查纽约市西班牙裔人群中结直肠癌的区域分布、该疾病不同亚部位发病的年龄,以及该疾病的发病频率是否存在两性差异。回顾了1976年至1995年纽约市贝尔维尤医院中心肿瘤登记处存档的西班牙裔患者病历。分析了包括患者年龄和癌症位置在内的人口统计学和病理学数据。远端结肠和直肠病变占比超过70%,而右侧病变见于20.7%的患者。男女比例为47.6%比52.4%。患者的总体平均年龄为60.4岁。近端病变的发病年龄晚于远端病变,右半结肠为63.2岁,直肠为58.5岁;年龄差异具有显著性。这些结果表明,患有结直肠癌的西班牙裔美国患者的发病年龄似乎比美国普通人群更早。需要进一步研究以确定西班牙裔女性结直肠癌的发病频率是否高于男性,以及西班牙裔患者的发病年龄是否比患有结直肠恶性肿瘤的普通人群更早,以及原因。