Elbahnasy A M, Shalhav A, Hoenig D M, Figenshau R, Clayman R V
Department of Surgery/Division of Urologic Surgery, Washington University School of Medicine, St. Louis, Missouri, USA.
J Urol. 1998 Mar;159(3):628-37.
We evaluate and compare the characteristics and drawbacks of different synthetic and organic materials that have been used for bladder wall replacement.
We extensively reviewed the contemporary literature for partial bladder wall replacement with synthetic or organic materials.
The concept of bladder wall replacement dates back to the early nineteenth century. Based on the unique regenerative capability of the bladder, many organic and synthetic allografts and xenografts were implanted in the bladder wall with a wide range of outcomes. Recently, various biodegradable allografts have been developed and used successfully in animal models. Despite the favorable animal results, only a few of the materials have been used clinically for bladder wall replacement to date.
Further improvements in the use of existing materials and development of new materials will hopefully result in clinically successful grafts for bladder wall replacement and for whole bladder substitution.
我们评估并比较了用于膀胱壁替代的不同合成材料和有机材料的特性及缺点。
我们广泛回顾了当代关于使用合成材料或有机材料进行部分膀胱壁替代的文献。
膀胱壁替代的概念可追溯到19世纪早期。基于膀胱独特的再生能力，许多有机和合成的同种异体移植物及异种移植物被植入膀胱壁，结果差异很大。最近，各种可生物降解的同种异体移植物已被开发并成功用于动物模型。尽管在动物实验中取得了良好结果，但迄今为止只有少数几种材料被临床用于膀胱壁替代。
现有材料使用方法的进一步改进以及新材料的开发有望带来临床上成功的用于膀胱壁替代和全膀胱置换的移植物。
