Chin J L, Downey D B, Mulligan M, Fenster A
Division of Urology, London Health Sciences Centre, Ontario, Canada.
J Urol. 1998 Mar;159(3):910-4.
A 3-dimensional (D) transrectal ultrasound imaging system was incorporated into the cryoablation routine for prostate cancer to assess its feasibility and use. The objective was to improve visibility for probe placement and for intraoperative monitoring.
A commercially available transrectal ultrasound unit was coupled with a custom designed software system to construct 3-dimensional prostate images. A total of 52 patients with clinically localized prostate cancer, in whom radiotherapy had failed (45) or who were otherwise judged to be nonsurgical candidates (7) were treated with cryoablation, using 3-D transrectal ultrasound for intraoperative guidance.
In all cases the intraoperative 3-D transrectal ultrasound images provided a unique coronal view of the prostate, revealing useful information and facilitating more precise probe placement and treatment monitoring. Early postoperative histological and biochemical results and complication rates compare well with other contemporary series.
Although the precise role of cryoablation in the management of prostate cancer remains unclear and long-term results are pending, incorporation of a 3-D transrectal ultrasound imaging system into the cryoablation routine proved to be feasible and appeared to be a worthwhile effort to facilitate the procedure, and deserves further evaluation.
将三维（3D）经直肠超声成像系统纳入前列腺癌冷冻消融程序，以评估其可行性和用途。目的是提高探头放置和术中监测的可视性。
将市售经直肠超声设备与定制软件系统相结合，构建前列腺三维图像。共有52例临床局限性前列腺癌患者接受了冷冻消融治疗，其中放疗失败的患者45例，或被判定为非手术候选者的患者7例，术中使用三维经直肠超声进行引导。
在所有病例中，术中三维经直肠超声图像提供了独特的前列腺冠状面视图，揭示了有用信息，有助于更精确地放置探头和进行治疗监测。术后早期的组织学和生化结果以及并发症发生率与其他当代系列研究相比情况良好。
尽管冷冻消融在前列腺癌治疗中的确切作用仍不明确，长期结果尚待观察，但将三维经直肠超声成像系统纳入冷冻消融程序被证明是可行的，似乎是一项有助于该操作的有价值的尝试，值得进一步评估。
