Zambarakji H J, Rauz S, Reynolds A, Joshi N, Simcock P R, Kinnear P E
Department of Ophthalmology, Charing Cross Hospital, London, UK.
Eye (Lond). 1997;11 ( Pt 5):635-8. doi: 10.1038/eye.1997.168.
The aim of the study was to assess and compare the degree of capsulorhexis phymosis following uncomplicated phacoemulsification cataract surgery in polymethylmethacrylate (PMMA) and silicone lens implants.
Sixty-four patients were evaluated 1 day, 6 weeks and 6 months following phacoemulsification cataract extraction. The anterior capsular diameters were measured with the illuminated beam of the slit lamp at 45 degrees and 135 degrees and the surface area of the opening calculated. We have measured and compared the change in the capsulorhexis size for both lens types and assessed its statistical significance with a paired Student's t-test.
A statistically significant contraction of the capsulorhexis was noted in all patients within the first 6 weeks (p < 0.001). Capsular contraction continued between 6 weeks and 6 months post-operatively but to a lesser extent (p < 0.05). The difference in the degree of phymosis between the first period (1 day to 6 weeks) and the second (6 weeks to 6 months) was statistically highly significant for all patients (p < 0.001). The capsular areas for the silicone lens implants were significantly smaller than for the PMMA implants at 6 weeks and 6 months. None of our patients had a clinically significant capsular contracture requiring Nd:YAG laser capsulotomy.
Anterior capsular contraction is commonly observed following capsulorhexis in phacoemulsification surgery. This study demonstrates that the maximum rate of contraction occurs in the first 6 weeks following surgery and is more pronounced with silicone lens implants.
本研究旨在评估并比较聚甲基丙烯酸甲酯（PMMA）和硅胶人工晶状体植入的白内障超声乳化吸除术后连续环形撕囊口缩窄的程度。
64例患者在白内障超声乳化吸除术后1天、6周和6个月进行评估。用裂隙灯的照明光束在45度和135度测量前囊直径，并计算开口的表面积。我们测量并比较了两种人工晶状体类型的连续环形撕囊口大小变化，并用配对t检验评估其统计学意义。
所有患者在术后6周内均出现了具有统计学意义的连续环形撕囊口收缩（p < 0.001）。术后6周与6个月之间连续环形撕囊口继续收缩，但程度较轻（p < 0.05）。所有患者在第一个阶段（1天至6周）和第二个阶段（6周至6个月）的缩窄程度差异具有高度统计学意义（p < 0.001）。在6周和6个月时，硅胶人工晶状体植入患者的囊袋面积明显小于PMMA人工晶状体植入患者。我们的患者中没有一例出现需要Nd:YAG激光囊膜切开术的具有临床意义的囊膜挛缩。
白内障超声乳化吸除术后连续环形撕囊后常观察到前囊收缩。本研究表明，收缩的最大速率发生在术后6周内，且硅胶人工晶状体植入患者更为明显。
